Berberine is an alkaloid found in a herb called barberry (Berberis vulgaris) and related plants as well as in goldenseal, oregon grape root and Chinese goldthread. This herb has long been used in chinese and ayurvedic medicine. Berberine has significant anti-fungal activity and is also effective against some kinds of bacteria. As with all previously covered anti-fungal's, berberine is reported to spare beneficial organisms such as lactobacilli species. An added benefit for some people is its anti-diarrheal action. Research has shown that berberine can effectively prevent candida species from producing an enzyme called lipase which they use to help them colonize 3 . Berberine has also been widely shown to have a powerful directly anti-fungal action 4,5 Cost of treatment with berberine is roughly equivalent to that of the fatty acids.
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